Several of our Surgeons are involved in extensive research activities using the iVis Suite. Many papers have received wide coverage on some of the most prestigious medical publications worldwide.



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Epithelial Thickness Profile Change After Combined Topography-Guided Transepithelial Photorefractive Keratectomy and Corneal Cross-linking in Treatment of Keratoconus
Xiangjun Chen, MD; Aleksandar Stojanovic, MD; Xiaorui Wang; Jing Liang, MD; Di Hu, MD; Tor Paaske Utheim, MD, PhD
Journal of Refractive Surgery, Vol. 32, No. 9:[626-634] 1 September 2016 Thursday

Topography-Guided Transepithelial Surface Ablation in the Treatment of Moderate to High Astigmatism
Xiangjun Chen, MD; Aleksandar Stojanovic, MD; David Simonsen, MD; Xiaorui Wang; Yanhua Liu; Tor Paaske Utheim, MD, PhD
Journal of Refractive Surgery, Vol. 32, No. 11:[418-425] 1 June 2016 Wednesday

Postoperative Changes in Corneal Epithelial and Stromal Thickness Profiles After Photorefractive Keratectomy in Treatment of Myopia
Xiangjun Chen, MD; Aleksandar Stojanovic, MD; Yanhua Liu, MD; Yunyun Chen, MD; Yang Zhou, MD; Tor Paaske Utheim, MD, PhD
Journal of Refractive Surgery, Vol. 31, (8) 20 May 2015

Corneal Collagen Cross-Linking with and without Epithelial Removal: A Contralateral Study with 0.5% Hypotonic Riboflavin Solution
Aleksandar Stojanovic, Wen Zhou, and Tor Paaske Utheim
Hindawi Publishing Corporation, Vol. 2014, (10) 2014

Reliability of Corneal Dynamic Scheimpflug Analyser Measurements in Virgin and Post-PRK Eyes
Xiangjun Chen, Aleksandar Stojanovic, Yanjun Hua, Jon Roger Eidet, DiHu, Jingting Wang, Tor Paaske Utheim
PLOS ONE, Vol. 9, (7), Issue 10 Octorber 2014

Confocal Microscopy Analysis of Corneal Changes After Photorefractive Keratectomy Plus Cross-Linking for Keratoconus: 4-Year Follow-up
Giovanni Alessio, Milena L'Abbate, Claudio Furino, Carlo Sborgia, Maria Gabriella La Tegola
Elsevier Inc., Vol. 158, (10) 21 May 2014

Clinical research on topography-guided transepithelial photorefractive keratectomy in the treatment of astigmatis after penetrating keratoplasty
JIN Nan, LIU Xu, CHEN Xiang-jun, Stojanovic Aleksander, XU Yue, ZHANG Ting, LU Fan
Chin J Ophthalmol Vis Sci, Vol. 15, No. 7 July 2013

One-Step Transepithelial Topography-Guided Ablation in the Treatment of Myopic Astigmatism.
Aleksandar Stojanovic mail, Shihao Chen, Xiangjun Chen, Filip Stojanovic, Jia Zhang, Ting Zhang, Tor Paaske Utheim
PLoS ONE 8(6): e66618. doi:10.1371/journal.pone.0066618 17 June 2013 Monday

Central Corneal Regularization – Optimization of Uncorrected Visual Acuity in Keratoconus Patients
C. Kaufmann, F. Bochmann, P. Baenninger, M. A. Thiel
Dept. Of Ophthalmology, Cantonal Hospital Lucerne, Lucerne, Switzerland (Chair: Michael A. Thiel) 6 January 2013

Photorefractive Keratectomy Followed by Cross-linking versus Cross-linking Alone for Management of Progressive Keratoconus: Two-Year Follow-up
G. Alessio MD, M. L’Abbate MD, C. Sborgia MD, M.G. La Tegola MD;
American Journal of Ophthalmology, Article in Press 16 September 2012 Saturday

Optical pachymetry–guided custom excimer laser-assisted lamellar keratoplasty for the surgical treatment of keratoconus
Leopoldo Spadea, MD; Riccardo Gizzi, MD; Nicole Evangelista Conocchia, MD; Sara Urbano, BS
Journal of Cataract & Refractive Surgery, Volume 38, Issue 9 15 September 2012 Saturday

Simultaneous topography-guided PRK followed by corneal collagen cross-linking after lamellar keratoplasty for keratoconus.
Leopoldo Spadea, MD; Marino Paroli, MD;
Clinical Ophthalmology, Dovepress, 1793-1800 01 June 2012 Friday

Effect of Limbal Marking Prior to Laser Ablation on the Magnitude of Cyclotorsional Error
Xiangjun Chen, MD, MS; Aleksandar Stojanovic, MD; Filip Stojanovic; Jon Roger Eidet, MD; Sten Raeder, MD, PhD; Haakon Øritsland, MD; Tor Paaske Utheim, MD, PhD
SLACK Incorporated, Vol. 28, No. 5, (5) 12 March 2012

Safety and Efficacy of Epithelium-On Corneal Collagen Cross-Linking Using a Multifactorial Approach to Achieve Proper Stromal Riboflavin Saturation
Aleksandar Stojanovic, Xiangjun Chen, Nan Jin, Ting Zhang, Filip Stojanovic, Sten Raeder, and Tor Paaske Utheim
Hindawi Publishing Corporation, Volume 2012, (9) 10 June 2012

Transepithelial, Topography-guided Ablation in the Treatment of Visual Disturbances in LASIK Flap or Interface Complications
Xiangjun Chen, MD, MS; Aleksandar Stojanovic, MD; Wen Zhou; Tor Paaske Utheim, MD, PhD; Filip Stojanovic; Qinmei Wang, MD
Journal of Refractive Surgery, Vol. 28, No. 2, 2012 2012

Irregular Astigmatism Regularizing the Cornea and iVIS Suite Approach to Treatment
Aleksandar Stojanovic, MD and Mirko R. Jankov II, MD, PhD
CHAPTER 22 2012

Custom transepithelial ablatiom versus photorefractive keratectomy with mechanical epithelial removal and comparision of postoperative pain, reepithelialization rate of recovery and early visual outcomes
ZHOU Wen, CHEN Xiang-jun, Aleksander STOJANOVIC, WANG Qin-mei;
Chin J Ophthalmol Vis Sci, Vol. 13, No. 4 August 2011

NO-TOUCH PRK Removing epithelium with laser speeds healing and reduces pain of corneal surface ablation
By Roibeard O’hEineachain in Paris
REFRACTIVE LASER, Special Focus, Vol. 16, Issue 3 2011

Refractive Correction With C-TEN
BY ISAAK SCHIPPER, MD; AND URS THOMANN, MD
REFRACTIVE SURGERY FEATURE STORY SEPTEMBER 2010

Cheratoplastica lamellare con laser ad eccimeri con customizzazione a guida pachimetrica nel trattamento del cheratocono
Leopoldo Spadea, MD; Arianna Fiasca MD, Riccardo Gizzi, MD
ViscoChirurgia 3 16 January 2010 Saturday

Topography-guided Tansepithelial Surface Abaltion Followed by Corneal Collagen Cross-linking Performed in a Single Combined Procedure for the Treatment of Keratoconus and Pellucid Marginal Degeneation
A. Stojanovic, MD; j. Zhang, MD; X. Chen, MD; T. Nitter, MD, PhD; S. Chen, MD; Q. Wang, MD
Journal of Refractive Surgery, Vol. 26 No. 2 16 January 2010 Saturday

Penetration of riboflavin and postoperative pain in corneal collagen crosslinking Excimer laser superficial versus mechanical full-thickness epithelial removal
Espen F. Bakke, MD, Aleksandar Stojanovic, MD, Xiangjun Chen, MD, Liv Drolsum, MD, PhD
Elsevier Inc., Vol. 39, (4) August 2009

New and Future Treatments Excimer Laser Lamellar Keratoplasty and Advanced Cross-linking
Leopoldo Spadea, MD; Dale P. Devore, PhD, Richard A. Eiferman, MD, FACS; Bruce Dewoolfson, PhD; Charles Wm. Stewart, OD; Tracy Swartz, OD, MS, FAAO; and Ming Wang, MD, PhD
Wang M, ed. Keratoconus & Keratoectasia: Prevention, Diagnosis, and Treatment (pp. 169–177) © 2009 SLACK Incorporated, Chapter 18. 16 May 2009 Saturday

Refractive Surgical Problem
Sonia H. Yoo, MD
Journal of Cataract and Refractive Surgery, Vol. 35 14 May 2009 Thursday

Cheratoplastica lamellare nel cheratocono e laser ad eccimeri
Leopoldo Spadea, Arianna Fiasca
La Voce AICCER March 2009

Excimer laser-assisted lamellar keratoplasty for the surgical treatment of keratoconus
Leopoldo Spadea, MD, Daniele Giammaria, MD, Arianna Fiasca, MD, Valerio Verrecchia, MD
J Cataract Refract Surg 2009 ASCRS and ESCRS 2009

Residual Astigmatism After Corneal Ablation
Cataract & Refractive Surgery Today Europe
L. Spadea, MD 16 October 2008 Thursday

Treatment of Irregular Astigmatism: Developing an Ideal Corneal Surface with the iVis Suite.
Ming Wang, MD, PhD; Tracy Swartz, OD, MD, FAAO (Eds.). Aleksandar Stojanovic , MD and Mirko R. Jankov II, MD, PhD.
Management of Complications in Refractive Surgery Chapter 22 14 October 2008 Tuesday

Irregular Astigmatism: Diagnosis and Treatment. Chapter 12: Complications of Refractive Keratotomy
Jorge L. Aliò, MD; Dimitri T. Azar, MD (Eds.). Carlo F. Lovisolo, MD; Alessandro Mularoni, MD; Antonio Calossi, MD; Charles Wm. Stewart, OD.
Springer, Pages 197-224. 16 March 2008 Sunday

Atlas of Lamellar Keratoplasty. Optical pachymetry guided, excimer laser customised ablation, for lamellar keratoplasty
Leopoldo Spadea, MD; Arianna Fiasca, MD; Valerio Verrecchia, MD
Fabiano Editore. Pages 89-99. 16 November 2007 Friday

Custom Ablation for Irregular Astigmatism
BY ALEKSANDAR STOJANOVIC, MD
REFRACTIVE SURGERY FEATURE STORY MAY 2007

Customised Transepithelial Photorefractive Keratectomy for Iatrogenic Ametropia after Penetrating or Deep Lamellar Keratoplasty.
Emilio Pedrotti, MD; Arianna Sbabo, MD; Giorgio Marchini, MD
Journal of Cataract & Refractive Surgery, Volume 38, Issue 9 16 August 2006 Wednesday

Corneal Topography in the Wavefront Era.
Emilio Pedrotti, MD; Arianna Sbabo, MD; Giorgio Marchini, MD.
A Guide for Clinical Application, "Chapter 25: Precisio" 14 August 2006 Monday

Topography Guided Customised Treatments in Visually Disturbing Irregular Astigmatism - iVis System.
G Alessio, MD; MG La Tegola, MD; C. Sborgia, MD
ACTA Ophthalmologica Scandanavia, Volume 84, Issue s238, Page 9 16 June 2006 Friday

Fixing the Eye - iVis Approach
G Alessio, MD; MG La Tegola, MD; C. Sborgia, MD; R. Dima, MD
ACTA Ophthalmologica Scandanavia, Volume 84, Issue s238, Page 71 14 June 2006 Wednesday

Two-step LASIK With Topography-guided Ablation to Correct Astigmatism After Penetrating Keratoplasty
Alessandro Mularoni, MD; Gian Luca Laffi, MD; Leona Bassein, Cstat; Giorgio Tassinari, MD
Journal of Refractive Surgery, Volume 22 14 February 2006 Tuesday

Enhancement outcomes after photorefractive keratectomy and laser in situ keratomileusis using topographically guided excimer laser photoablation
Leopoldo Spadea, MD, Angela Di Gregorio, MD
J CATARACT REFRACT SURG, VOL 31 DECEMBER 2005

Strategic Planning in Topography-guided Ablation of Irregular Astigmatism After Laser Refractive Surgery.
Aleksandar Stojanovic, MD; Dasa Suput, MD
Journal of Refractive Surgery, Volume 21 16 July 2005 Saturday

CIPTA Software Helps Treat Corneal Irregularities After Previous Refractive Surgery
Aleksandar Stojanovic, MD
Ocular Surgery News 15 September 2003 Monday

Corneal Interactive Programmed Topographic Ablation Customised Photorefractive Keratectomy for Correction of Postkeratoplasy Astigmatism.
Giovanni Alessio, MD; Francesco Boscia, MD; Maria Gabriella La Tegola, MD; Carlo Sborgia, MD
American Academy of Ophthalmology, Volume 108, Number 11 16 September 2001 Sunday

Topgraphy-driven Excimer Laser for the Retreatment of Decentralized Myopic Photorefractive Keratectomy
Giovanni Alessio, MD, Franceso Boscia, MD, Maria Gabriella La Tegola, MD, Carlo Sborgia, MD
Ophthalmology , Volume 108, Number 9 14 September 2001 Friday

Topography-driven Photorefractive Keratectomy
Givoanni Alessio, MD, Franceso Boscia, MD, Maria Gabriella La Tegola, MD, Carlo Sborgia, MD
American Academy of Ophtalmology Published, Ophthalmology Volume 107 Number 8, 10 01 Agust 2000